Study supports AB-Biotics probiotic blend to reduce colic

Adding to an existing scientific database exploring the role of probiotics in infantile colic, the results revealed that daily oral supplementation of AB-KOLICARE significantly improves symptoms of the disease, including time to cry, creating innovation opportunities in the field of infant nutrition.

Infant colic, also known as excessive crying syndrome, is a common disorder in infants one to five months of age, marked by frequent and prolonged crying or restlessness in otherwise healthy babies. Its etiology is unclear, but the evidence regarding the implications of infant gut microbiota and overall gut health is growing.

Previous studies have shown that in the gut microbiota of babies with colic there is usually a lower level of commensal bacteria like Lactobacilliand Bifidobacteriaand a higher number of proteobacteria. These findings have triggered a number of studies on the effect of supplementing the gut microbiota of colicky babies with products containing probiotic bacteria.

This latest double-blind, randomized controlled study investigated the impact of AB-KOLICARE administered daily orally – combining patented probiotic strains Bifidobacterium longumKABP-042 (CECT 7894) and Pediococcus pentosaceusKABP-041 (CECT 8330) – on symptoms of infantile colic.

Carried out in 112 exclusively breastfed or mixed-fed infants, it found that supplementation with AB-KOLICARE for 21 days reduced the time of crying and / or restlessness and fewer episodes of crying and / or agitation compared to the placebo group. It should be noted that although both groups showed a response, infants given the probiotic solution showed a clinically significant response in the first week compared to babies in the control group (83% vs. 36%), and despite the babies in both groups improving over time, the probiotic treatment offered better results by day 21.

Plus, the probiotic formula improved fecal consistency. It was therefore concluded that AB-KOLICARE is an effective solution for the prevention and treatment of infantile colic.

Colic can be an extremely distressing experience, both for babies and their families.Comments Jordi Riera, Business Development Director, AB-Biotics.

“Emerging research shows that babies with infantile colic have a different microbiota composition than those without. For example, the presence of Bifidobacterium – beneficial bacteria that digest dietary fiber, help prevent infections, and produce vitamins – is only 0.3% in colicky babies, compared to 10% in non-colic infants.

“This suggests that the gut microbiota may play an important role in disease development and explains why probiotics are being explored as a potential treatment due to their gut strengthening properties.

“In this study, the probiotic solution contained a strain of B. longum, which is a human resident bifidobacterium (HRB) and one of the most common bifidobacteria in healthy infants. This is important since most other probiotic solutions for infants contain non-HRBs such as B. animalis.

Source: Frontiers in pediatrics

Chen. K., et al

“Infant colic treated with Bifidobacterium longum CECT7894 and 2 Pediococcus pentosaceus CECT8330: a randomized, double-blind, placebo-controlled trial”

doi: 10.3389 / fped.2021.635176

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